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Structured report proposals from radiological data

The AI platform BIOMETRICA, developed by jung diagnostics and certified as a medical device, analyzes radiological data, quantifies the relevant assessment parameters, and produces a structured report proposal on this basis.

This standardizes the quality of assessment at a high level, independent of the reading physician, and accelerates the diagnostic process. Radiology thereby saves valuable time.

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Supported clinical questions

BIOMETRICA is continuously expanded. The following clinical questions are currently supported:

Workup of suspected dementia Workup of suspected multiple sclerosis MS follow-up examination

For this purpose, the following assessment parameters are computer-quantified and delivered, quality-assured, as part of a biomarker report as well as a structured report proposal:

  • Lesion quantification and localization
  • Disease-related brain volume loss (atrophy)

The technologies for computer-assisted quantification have been validated in extensive clinical studies and published in high-profile scientific-clinical journals. An overview of our publications can be found on the Clinical Research page.

Ten representative FLAIR slices of a cranial MRI examination with color-marked, automatically detected T2 lesions
Sample reportAutomatic lesion detection: ten representative FLAIR slices with color-highlighted T2 lesions detected and localized by Biometrica. Source: anonymized Biometrica report.

Components of a BIOMETRICA report

Depending on the clinical question, the reports comprise data on different biomarkers:

T2 and contrast-enhancing T1 lesions

The total number and volume of T2 lesions and the number of contrast-enhancing T1 lesions are reported — in addition, the localization is specified across four categories (juxtacortical, periventricular, deep white matter, infratentorial).

T2 lesion activity

If a prior examination is available, new or significantly enlarged lesions are listed and broken down by localization — all shown in a direct before-and-after comparison.

Brain volume loss rate

From qualified 3D-T1 sequences of at least two examinations, the loss rate is calculated and compared by age against a healthy cohort — with a confidence interval for reliable differentiation between age-related and disease-related loss.

Regional brain volume loss

Particularly for the early detection or exclusion of Alzheimer's dementia, the hippocampal volume is reported separately — including a comparison with the normal cohort adjusted for age and head size.

Chart: volumes of the frontal, temporal, occipital and parietal lobes of the patient, each plotted against an age-matched normal cohort, with a color-coded 3D rendering of the brain lobes
Sample reportExtended brain volumetry: the volumes of individual brain lobes (frontal, temporal, occipital, parietal) are plotted against a healthy normal cohort (95% range) and rendered in color in three dimensions. Source: anonymized Biometrica report.

Focal brain volume loss

To identify focal brain atrophy, we use voxel-based morphometry, in which each voxel is compared with a scanner-specific normal cohort. This provides a detailed overview of atrophic brain structures and is therefore particularly suited to the differential diagnosis of dementia.

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Questions about BIOMETRICA?

Our scientific and technical team of experts is happy to answer your questions.